跨学科的取向一直植根于传播政治经济学的基因之中。作为政治经济学和传播研究的交叉学科，传播政治经济学在诞生、发展和演变过程中受到各种社会运动和社会思潮的影响，也积极吸纳其他学科的理论和方法，产生了各种跨学科取向。传播政治经济学与种族研究的结合注重分析种族和传播的互相建构；女性主义和传播政治经济学的结合看到了传媒背后的男权政治和金钱控制；传播政治经济学与民族志的结合注重解释不同族群的传播现象和行为；传播政治经济学与文化研究也在争论和对话中走向融合，在不断的反省和自我批评中完善自身理论体系，与时俱进。

Interdisciplinary orientation is rooted in the gene of Political Economy of Communication. As the inter-discipline of political economy and communication studies, Political Economy of Communication is in?uenced by different kinds of social movements and social thinking in its birth, development and evolution, and absorbs actively theories and methods of other disciplines, then develops various interdisciplinary orientations. Political Economy of Communication combining with race studies focuses on analyzing the mutual construction of race and communication, Political Economy of Communication combining feminism recognizes the male politics and money control; Political Economy of Communication combining ethnography emphasizes explaining communication phenomena and behaviors of different ethnic groups; Political Economy of Communication converges with cultural studies in their discussion and conversation. In retrospection and self-criticism, Political Economy of Communication continues to improve its theory system and keeps up with the times.