This paper takes Chinese writer Mo Yan’s winning of the Nobel Prize in Literature in 2012 as a case study. Based on the theories of representation of the other, media framing and stereotype, this paper examines how the U.S. news media represent Mo Yan and his literary works. It finds that the referencing significance of Chinese writer and Chinese literature as the other has been largely consumed; moreover, its comparative significance compared with the western writer and the western literature has been nearly lost in the politicized and orientalized coverage by the U.S. news media.